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Senior Research Fellow / Research Fellow (Medicine)

Senior Research Fellow / Research Fellow (Medicine)

National University of SingaporeQueenstown, Otago, New Zealand
22 hours ago
Job description

Senior Research Fellow / Research Fellow (Medicine)

The National University of Singapore – Queenstown is the national research university of Singapore. Founded in 1905 as the Straits Settlements and the Federated Malay States Government Medical School, NUS is the oldest higher education institution in Singapore.

Job Description

The Yong Loo Lin School of Medicine (NUS) is recruiting a full-time Senior Research Fellow / Research Fellow (1-year contract, renewable).

Purpose of the Post

The position is for the Metabolic Liver Disease Lab in the Department of Medicine, Yong Loo Lin School of Medicine. This role explores functional genomic methods to understand better the molecular mechanisms of metabolic dysfunction-associated fatty liver disease (MAFLD). The Post Doc Scientist will have the opportunity to collaborate with various teams across the School of Medicine, including pathologists, hepatologists, and data scientists. The candidate should demonstrate technical experimental excellence as well as the capacity to lead the research team regarding research projects aimed at producing clinically translational applications.

Responsibilities

  • Assist PI in coordinating and leading multiple wet lab projects, proposing research directions and meeting key project milestones.
  • Facilitate research team development, optimization, and validation of in vitro mammalian cell-based assays related to metabolic diseases (e.g., cell culture, RNA / protein extraction, qPCR, western blotting and other metabolic-related assays).
  • Perform other related duties incidental to the work described herein (such as data analysis, ensuring validity and reliability of data, maintaining accurate and complete records of all findings, presenting findings to colleagues).
  • Assist PI with writing for ethics / grant application.
  • Assist PI with organizing and publishing findings in high impact academic journals of good reputation.

Qualifications

  • A PhD with 3 years relevant post-doctoral experience.
  • Understanding of the molecular / cellular basis of MAFLD, obesity and T2D (e.g., lipid metabolism dysregulation, insulin resistance, inflammatory pathways) is desired.
  • Experience in handling 2D and 3D cell cultures such as hepatocytes, adipocytes or skeletal muscle cells is essential.
  • Molecular Biology skills (RNA / protein extraction, qPCR, western blotting, IF) are essential.
  • Cell line and clinical data multi-omics familiarity (e.g., transcriptomics, proteomics analysis) is a strong plus.
  • Experience with gene perturbation tools, such as siRNA, shRNA and CRISPR / Cas9 is a strong plus.
  • Experience working with murine models is a strong plus.
  • Excellent writing, communication and presentation skills in English.
  • Highly organized and skills in working independently and creatively to solve experimental problems within time constraints.
  • Ability to oversee research directions for multiple projects and work in a multidisciplinary team.
  • Applicants should send the following documents by email to

  • @nus.edu.sg and please mention "Application for Senior Research Fellow -Metabolic Liver Disease Lab" in your email subject :
  • Cover letter highlighting relevant experience and career goals.
  • Curriculum Vitae, containing details of three named referees.
  • A complete NUS Personal Data Consent for Job Applicants (the form is available at NUS Personal Data Consent for Job Applicants).
  • More Information

    Location : Kent Ridge Campus

    Organization : Yong Loo Lin School of Medicine

    Department : Medicine

    Employee Referral Eligible : No

    Job requisition ID : 30593

    #J-18808-Ljbffr

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