Scientist, Laboratory of Chemical Biology and Functional Genomics (GIS)

Scientist, Laboratory of Chemical Biology and Functional Genomics (GIS)

Agency for Science, Technology and Research – Queenstown

The Yu Lab has an opening position for Scientist and are looking for a highly motivated Scientist to join our team and contribute to innovative RNA-targeted therapeutic discovery.

We are a chemical biology lab dedicated to translational research targeting cellular nucleic acids. This project is to engineer antisense oligonucleotides (ASOs) for gene-selective regulation, paving the way for precision medicine. By leveraging cutting-edge gene-targeting strategies, structural biology, sequencing technologies, and computational approaches, we aim to unlock RNA as precise therapeutic target, addressing diseases linked to genomic dysregulation and undruggable pathways.

Contract length : 13-month contract for the first instance

Responsibilities :

• Lead the design and optimize RNA-targeting strategies in cells.
• Lead in designing and conducting experiments related to CRISPR, small-molecule screening, and ASO development.
• Perform molecular biology experiments, including CRISPR-based gene regulation, plasmid construction, stable cell line establishment, and RNA-seq library preparation.
• Maintain lab operations, including reagent preparation, consumable ordering, budget tracking, and equipment maintenance.
• Engage in literature reviews, research discussions, and collaborative projects.
• Ensure project milestones are met and contribute to manuscript preparation.

Requirements :

We offer a highly competitive remuneration package and relocation assistance. Singapore is a vibrant, cosmopolitan city-state at the heart of Asia, known for its excellent quality of life, world-class research infrastructure, and strong government support for scientific innovation.

Equal Employment Opportunity : We are an equal opportunities employer and welcome applications from qualified candidates.

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